中文簡介

分子治療《分子療法》雜志是基因轉(zhuǎn)移、載體開發(fā)與設計、干細胞操作、基因、肽、蛋白、寡核苷酸的開發(fā)、細胞療法、疫苗開發(fā)、臨床前目標驗證、安全性/有效性研究和臨床試驗等領域的領先期刊。分子療法致力于促進遺傳學、醫(yī)學和生物技術的科學發(fā)展。出版重要的同行評審研究和前沿評論和評論，該雜志繼續(xù)吸引該領域的最佳材料。分子治療2015年影響因子為6.938。分子治療-方法和臨床發(fā)展分子治療方法和臨床發(fā)展的目標是建立在分子治療的成功之上，在分子治療的保護傘下發(fā)表重要的同行評審的方法和程序，以及在廣泛領域的轉(zhuǎn)化進展。在期刊范圍內(nèi)特別感興趣的主題包括:基因載體工程與生產(chǎn)靶向基因組編輯和工程方法多能細胞重編程和定向分化的方法與技術發(fā)展基因和細胞載體傳遞的方法用于基因、細胞治療和再生醫(yī)學的生物材料和納米顆粒的開發(fā)分析基因和細胞載體的生物分布和跟蹤新型和下一代載體的藥理學/毒理學研究細胞分離、工程、培養(yǎng)、擴增和移植的方法細胞加工、儲存和貯存，用于治療臨床前和QC/QA分析開發(fā)轉(zhuǎn)化和臨床推廣以及良好的生產(chǎn)流程和工藝開發(fā)臨床協(xié)議開發(fā)用于分析、建模或可視化生物數(shù)據(jù)的計算方法和生物信息學方法談判監(jiān)管審批流程，并獲得臨床試驗的批準

　　英文簡介

Molecular TherapyMolecular Therapy is the leading journal for research in the areas of gene transfer, vector development and design, stem cell manipulation, development of gene-, peptide-, protein-, oligonucleotide-, and cell-based therapeutics to correct genetic and acquired diseases, vaccine development, pre-clinical target validation, safety/efficacy studies, and clinical trials. Molecular Therapy is dedicated to promoting the sciences in genetics, medicine, and biotechnology. Publishing important peer-reviewed research and cutting-edge reviews and commentaries, the journal continues to attract the best material in the field. Molecular Therapy''s 2015 impact factor is 6.938.Molecular Therapy — Methods & Clinical DevelopmentsThe aim of Molecular Therapy—Methods & Clinical Development is to build upon the success of Molecular Therapy in publishing important peer-reviewed methods and procedures, as well as translational advances in the broad array of fields under the molecular therapy umbrella.Topics of particular interest within the journal''s scope include:Gene vector engineering and productionMethods for targeted genome editing and engineeringMethods and technology development for cell reprogramming and directed differentiation of pluripotent cellsMethods for gene and cell vector deliveryDevelopment of biomaterials and nanoparticles for applications in gene and cell therapy and regenerative medicineAnalysis of gene and cell vector biodistribution and trackingPharmacology/toxicology studies of new and next-generation vectorsMethods for cell isolation, engineering, culture, expansion, and transplantationCell processing, storage, and banking for therapeutic applicationPreclinical and QC/QA assay developmentTranslational and clinical scale-up and Good Manufacturing procedures and process developmentClinical protocol developmentComputational and bioinformatic methods for analysis, modeling, or visualization of biological dataNegotiating the regulatory approval process and obtaining such approval for clinical trials

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